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PR
2008
88views more  PR 2008»
13 years 6 months ago
Modified global k
Clustering in gene expression data sets is a challenging problem. Different algorithms for clustering of genes have been proposed. However due to the large number of genes only a ...
Adil M. Bagirov
BIOINFORMATICS
2007
137views more  BIOINFORMATICS 2007»
13 years 6 months ago
Annotation-based distance measures for patient subgroup discovery in clinical microarray studies
: Background Clustering algorithms are widely used in the analysis of microarray data. In clinical studies, they are often applied to find groups of co-regulated genes. Clustering...
Claudio Lottaz, Joern Toedling, Rainer Spang
BMCBI
2006
119views more  BMCBI 2006»
13 years 6 months ago
LS-NMF: A modified non-negative matrix factorization algorithm utilizing uncertainty estimates
Background: Non-negative matrix factorisation (NMF), a machine learning algorithm, has been applied to the analysis of microarray data. A key feature of NMF is the ability to iden...
Guoli Wang, Andrew V. Kossenkov, Michael F. Ochs
BMCBI
2006
143views more  BMCBI 2006»
13 years 6 months ago
Discovering functional gene expression patterns in the metabolic network of Escherichia coli with wavelets transforms
Background: Microarray technology produces gene expression data on a genomic scale for an endless variety of organisms and conditions. However, this vast amount of information nee...
Rainer König, Gunnar Schramm, Marcus Oswald, ...
SSDBM
2003
IEEE
123views Database» more  SSDBM 2003»
13 years 12 months ago
MoBIoS: A Metric-Space DBMS to Support Biological Discovery
MoBIoS is a specialized database management system whose storage manager is based on metric-space indexing, and whose query language entails biological data types. When relational...
Daniel P. Miranker, Weijia Xu, Rui Mao