We address the issue of providing highly informative annotations using information revealed by the structured vocabularies of Gene Ontology (GO). For a target, a set of candidate ...
Background: The most common substitution matrices currently used (BLOSUM and PAM) are based on protein sequences with average amino acid distributions, thus they do not represent ...
Abstract--Protein complexes are important for understanding principles of cellular organization and functions. With the availability of large amounts of high-throughput proteinprot...
Guimei Liu, Chern Han Yong, Limsoon Wong, Hon Nian...
Despite recent progress in high-throughput experimental studies, systems level visualization and analysis of large protein interaction networks (ppi) remains a challenging task, g...
Boon-Siew Seah, Sourav S. Bhowmick, Charles Forbes...
Background: Computational comparison of two protein structures is the starting point of many methods that build on existing knowledge, such as structure modeling (including modeli...