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» Clustering the annotation space of proteins
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BMCBI
2006
125views more  BMCBI 2006»
13 years 9 months ago
Automated functional classification of experimental and predicted protein structures
Background: Proteins that are similar in sequence or structure may perform different functions in nature. In such cases, function cannot be inferred from sequence or structural si...
Kai Wang, Ram Samudrala
BMCBI
2006
92views more  BMCBI 2006»
13 years 9 months ago
Similarity-based gene detection: using COGs to find evolutionarily-conserved ORFs
Background: Experimental verification of gene products has not kept pace with the rapid growth of microbial sequence information. However, existing annotations of gene locations c...
Bradford C. Powell, Clyde A. Hutchison III
NAR
2008
138views more  NAR 2008»
13 years 9 months ago
TarO: a target optimisation system for structural biology
TarO (http://www.compbio.dundee.ac.uk/taro) offers a single point of reference for key bioinformatics analyses relevant to selecting proteins or domains for study by structural bi...
Ian M. Overton, C. A. Johannes van Niekerk, Lester...
CSB
2005
IEEE
205views Bioinformatics» more  CSB 2005»
14 years 2 months ago
Fractal Clustering for Microarray Data Analysis
DNA microarray experiments generate a substantial amount of information about global gene expression. Gene expression profiles can be represented as points in multi-dimensional sp...
Lu-Yong Wang, Ammaiappan Balasubramanian, Amit Cha...
BMCBI
2011
13 years 4 months ago
A Computational Framework for Proteome-Wide Pursuit and Prediction of Metalloproteins using ICP-MS and MS/MS Data
Background: Metal-containing proteins comprise a diverse and sizable category within the proteomes of organisms, ranging from proteins that use metals to catalyze reactions to pro...
W. Andrew Lancaster, Jeremy L. Praissman, Farris L...