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BMCBI
2010
172views more  BMCBI 2010»
13 years 7 months ago
Comparison of evolutionary algorithms in gene regulatory network model inference
Background: The evolution of high throughput technologies that measure gene expression levels has created a data base for inferring GRNs (a process also known as reverse engineeri...
Alina Sîrbu, Heather J. Ruskin, Martin Crane
BMCBI
2010
138views more  BMCBI 2010»
13 years 7 months ago
A model-independent approach to infer hierarchical codon substitution dynamics
Background: Codon substitution constitutes a fundamental process in molecular biology that has been studied extensively. However, prior studies rely on various assumptions, e.g. r...
Olof Görnerup, Martin Nilsson Jacobi
BMCBI
2010
105views more  BMCBI 2010»
13 years 7 months ago
Comparison of PGH2 binding site in prostaglandin synthases
Background: Prostaglandin H2 (PGH2) is a common precursor for the synthesis of five different Prostanoids via specific Prostanoid Synthases. The binding of this substrate with the...
Padmapriya Paragi-Vedanthi, Mukesh Doble
BMCBI
2010
176views more  BMCBI 2010»
13 years 7 months ago
Reverse engineering gene regulatory network from microarray data using linear time-variant model
nd: Gene regulatory network is an abstract mapping of gene regulations in living cells that can help to predict the system behavior of living organisms. Such prediction capability...
Mitra Kabir, Nasimul Noman, Hitoshi Iba
BMCBI
2010
104views more  BMCBI 2010»
13 years 7 months ago
Bidirectional best hit r-window gene clusters
Background: Conserved gene clusters are groups of genes that are located close to one another in the genomes of several species. They tend to code for proteins that have a functio...
Melvin Zhang, Hon Wai Leong