Resolving the general organizational principles that govern the interactions during transcriptional gene regulation has great relevance for understanding disease progression, biof...
Background: We suggest a new type of modeling approach for the coarse grained, particle-based spatial simulation of combinatorially complex chemical reaction systems. In our appro...
Currently, most of the discovered biological and biomedical knowledge is available as textual data in scientific papers. And, locating and curating information about a genomic enti...
Background: Regulatory regions that function in DNA replication and gene transcription contain specific sequences that bind proteins as well as less-specific sequences in which th...
Negation is intrinsic to human thinking and most of the time when searching for something, we base our patterns on both positive and negative conditions. This should be naturally ...
Horatiu Cirstea, Claude Kirchner, Radu Kopetz, Pie...