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BMCBI
2005
94views more  BMCBI 2005»
13 years 8 months ago
Visualization-based discovery and analysis of genomic aberrations in microarray data
Background: Chromosomal copy number changes (aneuploidies) play a key role in cancer progression and molecular evolution. These copy number changes can be studied using microarray...
Chad L. Myers, Xing Chen, Olga G. Troyanskaya
BMCBI
2010
134views more  BMCBI 2010»
13 years 9 months ago
R-Gada: a fast and flexible pipeline for copy number analysis in association studies
Background: Genome-wide association studies (GWAS) using Copy Number Variation (CNV) are becoming a central focus of genetic research. CNVs have successfully provided target genom...
Roger Pique-Regi, Alejandro Cáceres, Juan R...
BIOINFORMATICS
2005
72views more  BIOINFORMATICS 2005»
13 years 8 months ago
Use of within-array replicate spots for assessing differential expression in microarray experiments
Motivation. Spotted arrays are often printed with probes in duplicate or triplicate, but current methods for assessing differential expression are not able to make full use of the...
Gordon K. Smyth, Joëlle Michaud, Hamish S. Sc...
NAR
2007
90views more  NAR 2007»
13 years 8 months ago
PigGIS: Pig Genomic Informatics System
Pig Genomic Information System (PigGIS) is a web-based depository of pig (Sus scrofa) genomic learning mainly engineered for biomedical research to locate pig genes from their hum...
Jue Ruan, Yiran Guo, Heng Li, Yafeng Hu, Fei Song,...
BMCBI
2010
151views more  BMCBI 2010»
13 years 9 months ago
BABAR: an R package to simplify the normalisation of common reference design microarray-based transcriptomic datasets
Background: The development of DNA microarrays has facilitated the generation of hundreds of thousands of transcriptomic datasets. The use of a common reference microarray design ...
Mark J. Alston, John Seers, Jay C. D. Hinton, Sach...