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» Combining microarrays and genetic analysis
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BMCBI
2008
105views more  BMCBI 2008»
13 years 10 months ago
SIGMA2: A system for the integrative genomic multi-dimensional analysis of cancer genomes, epigenomes, and transcriptomes
Background: High throughput microarray technologies have afforded the investigation of genomes, epigenomes, and transcriptomes at unprecedented resolution. However, software packa...
Raj Chari, Bradley P. Coe, Craig Wedseltoft, Marie...
BIOINFORMATICS
2010
170views more  BIOINFORMATICS 2010»
13 years 10 months ago
Joint estimation of DNA copy number from multiple platforms
DNA copy number variants (CNV) are gains and losses of segments of chromosomes, and comprise an important class of genetic variation. Recently, various microarray hybridization ba...
Nancy R. Zhang, Yasin Senbabaoglu, Jun Z. Li
BMCBI
2004
75views more  BMCBI 2004»
13 years 9 months ago
Joint analysis of two microarray gene-expression data sets to select lung adenocarcinoma marker genes
Background: Due to the high cost and low reproducibility of many microarray experiments, it is not surprising to find a limited number of patient samples in each study, and very f...
Hongying Jiang, Youping Deng, Huann-Sheng Chen, Li...
RECOMB
2002
Springer
14 years 10 months ago
A bayesian approach to transcript estimation from gene array data: the BEAM technique
We present a new statistically optimal approach to estimate transcript levels and ratios from one or more gene array experiments. The Bayesian Estimation of Array Measurements (BE...
Ron O. Dror, Jonathan G. Murnick, Nicola A. Rinald...
BMCBI
2010
170views more  BMCBI 2010»
13 years 10 months ago
Integrative analysis of gene expression and copy number alterations using canonical correlation analysis
Background: With the rapid development of new genetic measurement methods, several types of genetic alterations can be quantified in a high-throughput manner. While the initial fo...
Charlotte Soneson, Henrik Lilljebjörn, Thoas ...