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BMCBI
2005
135views more  BMCBI 2005»
13 years 9 months ago
A robust two-way semi-linear model for normalization of cDNA microarray data
Background: Normalization is a basic step in microarray data analysis. A proper normalization procedure ensures that the intensity ratios provide meaningful measures of relative e...
Deli Wang, Jian Huang, Hehuang Xie, Liliana Manzel...
BMCBI
2008
242views more  BMCBI 2008»
13 years 9 months ago
annot8r: GO, EC and KEGG annotation of EST datasets
Background: The expressed sequence tag (EST) methodology is an attractive option for the generation of sequence data for species for which no completely sequenced genome is availa...
Ralf Schmid, Mark L. Blaxter
ISCI
2008
93views more  ISCI 2008»
13 years 9 months ago
Safety, domain independence and translation of complex value database queries
This paper considers the theory of database queries on the complex value data model with external functions. Motivated by concerns regarding query evaluation, we first identify re...
Hong-Cheu Liu, Jeffrey Xu Yu, Weifa Liang
BMCBI
2008
200views more  BMCBI 2008»
13 years 9 months ago
Defining functional distances over Gene Ontology
Background: A fundamental problem when trying to define the functional relationships between proteins is the difficulty in quantifying functional similarities, even when well-stru...
Angela del Pozo, Florencio Pazos, Alfonso Valencia
BMCBI
2004
149views more  BMCBI 2004»
13 years 8 months ago
MiCoViTo: a tool for gene-centric comparison and visualization of yeast transcriptome states
Background: Information obtained by DNA microarray technology gives a rough snapshot of the transcriptome state, i.e., the expression level of all the genes expressed in a cell po...
Gaëlle Lelandais, Philippe Marc, Pierre Vince...