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153
Voted
BMCBI
2005
152views more  BMCBI 2005»
15 years 4 months ago
Improved profile HMM performance by assessment of critical algorithmic features in SAM and HMMER
Background: Profile hidden Markov model (HMM) techniques are among the most powerful methods for protein homology detection. Yet, the critical features for successful modelling ar...
Markus Wistrand, Erik L. L. Sonnhammer
161
Voted
BMCBI
2008
119views more  BMCBI 2008»
15 years 4 months ago
Snagger: A user-friendly program for incorporating additional information for tagSNP selection
Background: There has been considerable effort focused on developing efficient programs for tagging single-nucleotide polymorphisms (SNPs). Many of these programs do not account f...
Christopher K. Edlund, Won H. Lee, Dalin Li, David...
126
Voted
IPPS
2009
IEEE
15 years 11 months ago
Exploring FPGAs for accelerating the phylogenetic likelihood function
Driven by novel biological wet lab techniques such as pyrosequencing there has been an unprecedented molecular data explosion over the last 2-3 years. The growth of biological seq...
Nikolaos Alachiotis, Euripides Sotiriades, Apostol...
BIBM
2008
IEEE
107views Bioinformatics» more  BIBM 2008»
15 years 11 months ago
A Functional Network of Yeast Genes Using Gene Ontology Information
In the post-genomic era, the organization of genes into networks has played an important role in characterizing the functions of individual genes and the interplay between them. I...
Erliang Zeng, Giri Narasimhan, Lisa Schneper, Kala...
GECCO
2007
Springer
256views Optimization» more  GECCO 2007»
15 years 10 months ago
A particle swarm optimization approach for estimating parameter confidence regions
Point estimates of the parameters in real world models convey valuable information about the actual system. However, parameter comparisons and/or statistical inference requires de...
Praveen Koduru, Stephen Welch, Sanjoy Das