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» Comparative genome assembly
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128
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BMCBI
2004
96views more  BMCBI 2004»
15 years 3 months ago
Gene finding in novel genomes
Background: Computational gene prediction continues to be an important problem, especially for genomes with little experimental data. Results: I introduce the SNAP gene finder whi...
Ian Korf
130
Voted
ISMB
1998
15 years 5 months ago
Sequence Assembly Validation by Multiple Restriction Digest Fragment Coverage Analysis
DNA sequence analysis depends on the accurate assembly of fragment reads for the determination of a consensus sequence. This report examines the possibility of analyzing multiple,...
Eric C. Rouchka, David J. States
129
Voted
ICDT
2003
ACM
150views Database» more  ICDT 2003»
15 years 9 months ago
Bioinformatics Adventures in Database Research
Informatics has helped launch molecular biology into the genomic era. It appears certain that informatics will remain a major contributor to molecular biology in the post-genome er...
Jinyan Li, See-Kiong Ng, Limsoon Wong
118
Voted
RECOMB
2005
Springer
16 years 4 months ago
On Sorting by Translocations
The study of genome rearrangements is an important tool in comparative genomics. This paper revisits the problem of sorting a multichromosomal genome by translocations, i.e. exchan...
Anne Bergeron, Julia Mixtacki, Jens Stoye
150
Voted
BMCBI
2010
189views more  BMCBI 2010»
15 years 3 months ago
Efficient parallel and out of core algorithms for constructing large bi-directed de Bruijn graphs
Background: Assembling genomic sequences from a set of overlapping reads is one of the most fundamental problems in computational biology. Algorithms addressing the assembly probl...
Vamsi Kundeti, Sanguthevar Rajasekaran, Hieu Dinh,...