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BMCBI
2008
112views more  BMCBI 2008»
13 years 8 months ago
Evaluation of genomic island predictors using a comparative genomics approach
Background: Genomic islands (GIs) are clusters of genes in prokaryotic genomes of probable horizontal origin. GIs are disproportionately associated with microbial adaptations of m...
Morgan G. I. Langille, William W. L. Hsiao, Fiona ...
IMSCCS
2006
IEEE
14 years 2 months ago
Combining Comparative Genomics with de novo Motif Discovery to Identify Human Transcription Factor DNA-Binding Motifs
Background: As more and more genomes are sequenced, comparative genomics approaches provide a methodology for identifying conserved regulatory elements that may be involved in gen...
Linyong Mao, W. Jim Zheng
BMCBI
2010
101views more  BMCBI 2010»
13 years 8 months ago
Comparative analysis of thermophilic and mesophilic proteins using Protein Energy Networks
Background: Thermophilic proteins sustain themselves and function at higher temperatures. Despite their structural and functional similarities with their mesophilic homologues, th...
M. S. Vijayabaskar, Saraswathi Vishveshwara
BMCBI
2006
127views more  BMCBI 2006»
13 years 8 months ago
Construction of phylogenetic trees by kernel-based comparative analysis of metabolic networks
Background: To infer the tree of life requires knowledge of the common characteristics of each species descended from a common ancestor as the measuring criteria and a method to c...
Sok June Oh, Je-Gun Joung, Jeong Ho Chang, Byoung-...
RECOMB
2003
Springer
14 years 9 months ago
Whole-genome comparative annotation and regulatory motif discovery in multiple yeast species
In [13] we reported the genome sequences of S. paradoxus, S. mikatae and S. bayanus and compared these three yeast species to their close relative, S. cerevisiae. Genome-wide comp...
Manolis Kamvysselis, Nick Patterson, Bruce Birren,...