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BIBE
2006
IEEE
154views Bioinformatics» more  BIBE 2006»
14 years 3 months ago
Determining Molecular Similarity for Drug Discovery using the Wavelet Riemannian Metric
Discerning the similarity between two molecules is a challenging problem in drug discovery as well as in molecular biology. The importance of this problem is due to the fact that ...
Elinor Velasquez, Emmanuel R. Yera, Rahul Singh
VLDB
2007
ACM
126views Database» more  VLDB 2007»
14 years 9 months ago
Querying Complex Structured Databases
Correctly generating a structured query (e.g., an XQuery or a SQL query) requires the user to have a full understanding of the database schema, which can be a daunting task. Alter...
Cong Yu, H. V. Jagadish
BMCBI
2006
175views more  BMCBI 2006»
13 years 9 months ago
Parameter estimation for stiff equations of biosystems using radial basis function networks
Background: The modeling of dynamic systems requires estimating kinetic parameters from experimentally measured time-courses. Conventional global optimization methods used for par...
Yoshiya Matsubara, Shinichi Kikuchi, Masahiro Sugi...
GECCO
2010
Springer
187views Optimization» more  GECCO 2010»
14 years 1 months ago
The maximum hypervolume set yields near-optimal approximation
In order to allow a comparison of (otherwise incomparable) sets, many evolutionary multiobjective optimizers use indicator functions to guide the search and to evaluate the perfor...
Karl Bringmann, Tobias Friedrich
IPPS
2000
IEEE
14 years 1 months ago
Reduction Optimization in Heterogeneous Cluster Environments
Network of workstation (NOW) is a cost-effective alternative to massively parallel supercomputers. As commercially available off-the-shelf processors become cheaper and faster, ...
Pangfeng Liu, Da-Wei Wang