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» Comparing Sequences with Segment Rearrangements
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ITNG
2007
IEEE
14 years 1 months ago
Sorting by Block-Interchanges and Signed Reversals
A block-interchange is a rearrangement event that exchanges two, not necessarily consecutive, contiguous regions in a genome, maintaining the original orientation. Signed reversal...
Cleber V. G. Mira, Joao Meidanis
RECOMB
2003
Springer
14 years 7 months ago
Transforming men into mice: the Nadeau-Taylor chromosomal breakage model revisited
Although analysis of genome rearrangements was pioneered by Dobzhansky and Sturtevant 65 years ago, we still know very little about the rearrangement events that produced the exis...
Pavel A. Pevzner, Glenn Tesler
JCB
2007
146views more  JCB 2007»
13 years 7 months ago
MSOAR: A High-Throughput Ortholog Assignment System Based on Genome Rearrangement
The assignment of orthologous genes between a pair of genomes is a fundamental and challenging problem in comparative genomics, since many computational methods for solving variou...
Zheng Fu, Xin Chen, Vladimir Vacic, Peng Nan, Yang...
BMCBI
2006
192views more  BMCBI 2006»
13 years 7 months ago
Analysis of circular genome rearrangement by fusions, fissions and block-interchanges
Background: Analysis of genomes evolving via block-interchange events leads to a combinatorial problem of sorting by block-interchanges, which has been studied recently to evaluat...
Chin Lung Lu, Yen-Lin Huang, Tsui Ching Wang, Hsie...
RECOMB
2005
Springer
14 years 7 months ago
A Framework for Orthology Assignment from Gene Rearrangement Data
Abstract. Gene rearrangements have been used successfully in phylogenetic reconstruction and comparative genomics, but usually under the assumption that all genomes have the same g...
Krister M. Swenson, Nicholas D. Pattengale, Bernar...