Discriminating between secreted and membrane proteins is a challenging task. This is particularly true for discriminating between transmembrane segments and signal peptides because...
Membrane proteins are an important class of proteins that serve as channels, receptors, and energy transducers in a cell membrane. Knowledge of a given type of cell membrane prote...
Seyed Koosha Golmohammadi, Lukasz A. Kurgan, Brend...
Background: Prediction of disulfide bridges from protein sequences is useful for characterizing structural and functional properties of proteins. Several methods based on differen...
Marc Vincent, Andrea Passerini, Matthieu Labb&eacu...
Background: Existing hidden Markov model decoding algorithms do not focus on approximately identifying the sequence feature boundaries. Results: We give a set of algorithms to com...
— The ability to identify protein binding sites and to detect specific amino acid residues that contribute to the specificity and affinity of protein interactions has importan...