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BMCBI
2008
86views more  BMCBI 2008»
13 years 8 months ago
Subfamily specific conservation profiles for proteins based on n-gram patterns
Background: A new algorithm has been developed for generating conservation profiles that reflect the evolutionary history of the subfamily associated with a query sequence. It is ...
John K. Vries, Xiong Liu
BMCBI
2006
114views more  BMCBI 2006»
13 years 8 months ago
Evaluation and comparison of mammalian subcellular localization prediction methods
Background: Determination of the subcellular location of a protein is essential to understanding its biochemical function. This information can provide insight into the function o...
Josefine Sprenger, J. Lynn Fink, Rohan D. Teasdale
EC
2006
121views ECommerce» more  EC 2006»
13 years 8 months ago
A Study of Structural and Parametric Learning in XCS
The performance of a learning classifier system is due to its two main components. First, it evolves new structures by generating new rules in a genetic process; second, it adjust...
Tim Kovacs, Manfred Kerber
BMCBI
2005
97views more  BMCBI 2005»
13 years 8 months ago
Evolutionary distance estimation and fidelity of pair wise sequence alignment
Background: Evolutionary distances are a critical measure in comparative genomics and molecular evolutionary biology. A simulation study was used to examine the effect of alignmen...
Michael S. Rosenberg
BMCBI
2005
125views more  BMCBI 2005»
13 years 8 months ago
DIALIGN-T: An improved algorithm for segment-based multiple sequence alignment
Background: We present a complete re-implementation of the segment-based approach to multiple protein alignment that contains a number of improvements compared to the previous ver...
Amarendran R. Subramanian, Jan Weyer-Menkhoff, Mic...