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» Comparing notions of randomness
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BMCBI
2008
155views more  BMCBI 2008»
13 years 8 months ago
Extending pathways based on gene lists using InterPro domain signatures
Background: High-throughput technologies like functional screens and gene expression analysis produce extended lists of candidate genes. Gene-Set Enrichment Analysis is a commonly...
Florian Hahne, Alexander Mehrle, Dorit Arlt, Annem...
BMCBI
2008
153views more  BMCBI 2008»
13 years 8 months ago
Estimating the size of the solution space of metabolic networks
Background: Cellular metabolism is one of the most investigated system of biological interactions. While the topological nature of individual reactions and pathways in the network...
Alfredo Braunstein, Roberto Mulet, Andrea Pagnani
BMCBI
2008
78views more  BMCBI 2008»
13 years 8 months ago
Evaluation of time profile reconstruction from complex two-color microarray designs
Background: As an alternative to the frequently used "reference design" for two-channel microarrays, other designs have been proposed. These designs have been shown to b...
Ana C. Fierro, Raphael Thuret, Kristof Engelen, Gi...
BMCBI
2010
193views more  BMCBI 2010»
13 years 8 months ago
MZmine 2: Modular framework for processing, visualizing, and analyzing mass spectrometry-based molecular profile data
Background: Mass spectrometry (MS) coupled with online separation methods is commonly applied for differential and quantitative profiling of biological samples in metabolomic as w...
Tomás Pluskal, Sandra Castillo, Alejandro V...
BMCBI
2008
162views more  BMCBI 2008»
13 years 8 months ago
Improved identification of conserved cassette exons using Bayesian networks
Background: Alternative splicing is a major contributor to the diversity of eukaryotic transcriptomes and proteomes. Currently, large scale detection of alternative splicing using...
Rileen Sinha, Michael Hiller, Rainer Pudimat, Ulri...