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BMCBI
2010
137views more  BMCBI 2010»
13 years 7 months ago
Improving pairwise sequence alignment accuracy using near-optimal protein sequence alignments
Background: While the pairwise alignments produced by sequence similarity searches are a powerful tool for identifying homologous proteins - proteins that share a common ancestor ...
Michael L. Sierk, Michael E. Smoot, Ellen J. Bass,...
BMCBI
2006
139views more  BMCBI 2006»
13 years 7 months ago
Improvement in accuracy of multiple sequence alignment using novel group-to-group sequence alignment algorithm with piecewise li
Background: Multiple sequence alignment (MSA) is a useful tool in bioinformatics. Although many MSA algorithms have been developed, there is still room for improvement in accuracy...
Shinsuke Yamada, Osamu Gotoh, Hayato Yamana
BMCBI
2008
140views more  BMCBI 2008»
13 years 7 months ago
SCPRED: Accurate prediction of protein structural class for sequences of twilight-zone similarity with predicting sequences
Background: Protein structure prediction methods provide accurate results when a homologous protein is predicted, while poorer predictions are obtained in the absence of homologou...
Lukasz A. Kurgan, Krzysztof J. Cios, Ke Chen 0003
RECOMB
2001
Springer
14 years 7 months ago
A new approach to sequence comparison: normalized sequence alignment
The Smith-Waterman algorithm for local sequence alignment is one of the most important techniques in computational molecular biology. This ingenious dynamic programming approach w...
Abdullah N. Arslan, Ömer Egecioglu, Pavel A. ...
CCGRID
2005
IEEE
14 years 1 months ago
Secret sequence comparison on public grid computing resources
Once a new gene has been sequenced, it must be verified whether or not it is similar to previously sequenced genes. In many cases, the organization that sequenced a potentially n...
Ken-ichi Kurata, Hiroshi Nakamura, Vincent Breton