2345 search results - page 312 / 469 » Comparing sequence scaffolds |
BMCBI
2008
13 years 8 months ago
2008
Background: Structural alignment is an important step in protein comparison. Well-established methods exist for solving this problem under the assumption that the structures under...
BMCBI
2008
13 years 8 months ago
2008
Background: Identifying the active site of an enzyme is a crucial step in functional studies. While protein sequences and structures can be experimentally characterized, determini...
BMCBI
2008
13 years 8 months ago
2008
Background: It is useful to develop a tool that would effectively describe protein mutation matrices specifically geared towards the identification of mutations that produce eithe...
BMCBI
2008
13 years 8 months ago
2008
Background: The development and improvement of reliable computational methods designed to evaluate the quality of protein models is relevant in the context of protein structure re...
BMCBI
2006
13 years 8 months ago
2006
Background: Hidden Markov Models (HMMs) have been extensively used in computational molecular biology, for modelling protein and nucleic acid sequences. In many applications, such...