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BMCBI
2004
13 years 7 months ago
2004
Background: A major goal of cancer research is to identify discrete biomarkers that specifically characterize a given malignancy. These markers are useful in diagnosis, may identi...
BMCBI
2004
13 years 7 months ago
2004
Background: Signal transduction is one of the most important biological processes by which cells convert an external signal into a response. Novel computational approaches to mapp...
BMCBI
2004
13 years 7 months ago
2004
Background: The rapidly increasing number of completely sequenced genomes led to the establishment of the COG-database which, based on sequence homologies, assigns similar protein...
BMCBI
2004
13 years 7 months ago
2004
Background: Certain protein families are highly conserved across distantly related organisms and belong to large and functionally diverse superfamilies. The patterns of conservati...
BMCBI
2004
13 years 7 months ago
2004
Background: Large-scale sequence comparison is a powerful tool for biological inference in modern molecular biology. Comparing new sequences to those in annotated databases is a u...