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EVOW
2008
Springer
13 years 10 months ago
Divide, Align and Full-Search for Discovering Conserved Protein Complexes
Advances in modern technologies for measuring protein-protein interaction (PPI) has boosted research in PPI networks analysis and comparison. One of the challenging problems in com...
Pavol Jancura, Jaap Heringa, Elena Marchiori
CGF
2010
146views more  CGF 2010»
13 years 8 months ago
Pathline: A Tool For Comparative Functional Genomics
Biologists pioneering the new field of comparative functional genomics attempt to infer the mechanisms of gene regulation by looking for similarities and differences of gene activ...
Miriah D. Meyer, Bang Wong, Mark P. Styczynski, Ta...
BMCBI
2006
120views more  BMCBI 2006»
13 years 8 months ago
Optimizing amino acid substitution matrices with a local alignment kernel
Background: Detecting remote homologies by direct comparison of protein sequences remains a challenging task. We had previously developed a similarity score between sequences, cal...
Hiroto Saigo, Jean-Philippe Vert, Tatsuya Akutsu
SC
2004
ACM
14 years 2 months ago
A Performance and Scalability Analysis of the BlueGene/L Architecture
This paper is structured as follows. Section 2 gives an architectural description of BlueGene/L. Section 3 analyzes the issue of “computational noise” – the effect that the o...
Kei Davis, Adolfy Hoisie, Greg Johnson, Darren J. ...
BMCBI
2008
110views more  BMCBI 2008»
13 years 8 months ago
Determining significance of pairwise co-occurrences of events in bursty sequences
Background: Event sequences where different types of events often occur close together arise, e.g., when studying potential transcription factor binding sites (TFBS, events) of ce...
Niina Haiminen, Heikki Mannila, Evimaria Terzi