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» Comparison of protein structures by growing neighborhood ali...
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NAR
2006
119views more  NAR 2006»
13 years 6 months ago
HHsenser: exhaustive transitive profile search using HMM-HMM comparison
HHsenser is the first server to offer exhaustive intermediate profile searches, which it combines with pairwise comparison of hidden Markov models. Starting from a single protein ...
Johannes Söding, Michael Remmert, Andreas Bie...
CPM
1993
Springer
154views Combinatorics» more  CPM 1993»
13 years 10 months ago
On Suboptimal Alignments of Biological Sequences
It is widely accepted that the optimal alignment between a pair of proteins or nucleic acid sequences that minimizes the edit distance may not necessarily re ect the correct biolog...
Dalit Naor, Douglas L. Brutlag
BMCBI
2006
80views more  BMCBI 2006»
13 years 6 months ago
Quantification of the variation in percentage identity for protein sequence alignments
Background: Percentage Identity (PID) is frequently quoted in discussion of sequence alignments since it appears simple and easy to understand. However, although there are several...
G. P. S. Raghava, Geoffrey J. Barton
BMCBI
2008
104views more  BMCBI 2008»
13 years 6 months ago
Analyzing the simplicial decomposition of spatial protein structures
Background: The fast growing Protein Data Bank contains the three-dimensional description of more than 45000 protein- and nucleic-acid structures today. The large majority of the ...
Rafael Ördög, Zoltan Szabadka, Vince Gro...
BMCBI
2005
138views more  BMCBI 2005»
13 years 6 months ago
Detailed protein sequence alignment based on Spectral Similarity Score (SSS)
Background: The chemical property and biological function of a protein is a direct consequence of its primary structure. Several algorithms have been developed which determine ali...
Kshitiz Gupta, Dina Thomas, S. V. Vidya, K. V. Ven...