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» Comparisons of Protein Family Dynamics
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WABI
2009
Springer
142views Bioinformatics» more  WABI 2009»
14 years 3 months ago
Back-Translation for Discovering Distant Protein Homologies
Background: Frameshift mutations in protein-coding DNA sequences produce a drastic change in the resulting protein sequence, which prevents classic protein alignment methods from ...
Marta Gîrdea, Laurent Noé, Gregory Ku...
BMCBI
2005
149views more  BMCBI 2005»
13 years 8 months ago
The PD-(D/E)XK superfamily revisited: identification of new members among proteins involved in DNA metabolism and functional pre
Background: The PD-(D/E)XK nuclease superfamily, initially identified in type II restriction endonucleases and later in many enzymes involved in DNA recombination and repair, is o...
Jan Kosinski, Marcin Feder, Janusz M. Bujnicki
GECCO
2005
Springer
162views Optimization» more  GECCO 2005»
14 years 2 months ago
Discovering biological motifs with genetic programming
Choosing the right representation for a problem is important. In this article we introduce a linear genetic programming approach for motif discovery in protein families, and we al...
Rolv Seehuus, Amund Tveit, Ole Edsberg
NAR
2007
90views more  NAR 2007»
13 years 8 months ago
The SUPERFAMILY database in 2007: families and functions
The SUPERFAMILY database provides protein domain assignments, at the SCOP ‘superfamily’ level, for the predicted protein sequences in over 400 completed genomes. A superfamily...
Derek Wilson, Martin Madera, Christine Vogel, Cyru...
NAR
2007
120views more  NAR 2007»
13 years 8 months ago
TOPOFIT-DB, a database of protein structural alignments based on the TOPOFIT method
TOPOFIT-DB (T-DB) is a public web-based database of protein structural alignments based on the TOPOFIT method, providing a comprehensive resource for comparative analysis of prote...
Chesley M. Leslin, Alexej Abyzov, Valentin A. Ilyi...