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» Comparisons of Protein Family Dynamics
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RIVF
2008
13 years 10 months ago
Speeding up subset seed algorithm for intensive protein sequence comparison
Abstract--Sequence similarity search is a common and repeated task in molecular biology. The rapid growth of genomic databases leads to the need of speeding up the treatment of thi...
Van Hoa Nguyen, Dominique Lavenier
BIRD
2007
Springer
120views Bioinformatics» more  BIRD 2007»
14 years 2 months ago
Joining Softassign and Dynamic Programming for the Contact Map Overlap Problem
Comparison of 3-dimensional protein folds is a core problem in molecular biology. The Contact Map Overlap (CMO) scheme provides one of the most common measures for protein structur...
Brijnesh J. Jain, Michael Lappe
JCB
1998
92views more  JCB 1998»
13 years 8 months ago
Homology Detection via Family Pairwise Search
The function of an unknown biological sequence can often be accurately inferred by identifying sequences homologous to the original sequence. Given a query set of known homologs, ...
William Noble Grundy
ISMB
1997
13 years 10 months ago
Identifying Chimerism in Proteins Using Hidden Markov Models of Codon Usage
Protein chimerism is a phenomenon involving the combination of multiple ancestral sequences into a single, multi-domain protein through evolution. We propose a novel method for de...
Lawrence Hunter, Barry Zeeberg
JCB
2000
107views more  JCB 2000»
13 years 8 months ago
A Discriminative Framework for Detecting Remote Protein Homologies
A new method for detecting remote protein homologies is introduced and shown to perform well in classifying protein domains by SCOP superfamily. The method is a variant of support...
Tommi Jaakkola, Mark Diekhans, David Haussler