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CIBCB
2006
IEEE
14 years 2 months ago
E2D: A Novel Tool for Annotating Protein Domains in Expressed Sequence Tags
The vast number of expressed sequence tags (ESTs) in public databases provides an important resource for comparative and functional genomics. A variety of methods based on homology...
Guo-Hsing Lee, Nai-Yu Chuang, Wen-Dar Lin, Chung-D...
BMCBI
2004
141views more  BMCBI 2004»
13 years 8 months ago
Estimates of statistical significance for comparison of individual positions in multiple sequence alignments
Background: Profile-based analysis of multiple sequence alignments (MSA) allows for accurate comparison of protein families. Here, we address the problems of detecting statistical...
Ruslan Sadreyev, Nick V. Grishin
BMCBI
2011
13 years 10 days ago
GPCR-SSFE: A comprehensive database of G-protein-coupled receptor template predictions and homology models
Background: G protein-coupled receptors (GPCRs) transduce a wide variety of extracellular signals to within the cell and therefore have a key role in regulating cell activity and ...
Catherine L. Worth, Annika Kreuchwig, Gunnar Klein...
COMPLIFE
2005
Springer
14 years 2 months ago
Protein Annotation by Secondary Structure Based Alignments (PASSTA)
Abstract. Most software tools in homology recognition on proteins answer only a few specific questions, often leaving not much room for the interpretation of the results. We devel...
Constantin Bannert, Jens Stoye
BMCBI
2008
138views more  BMCBI 2008»
13 years 8 months ago
Using neural networks and evolutionary information in decoy discrimination for protein tertiary structure prediction
Background: We present a novel method of protein fold decoy discrimination using machine learning, more specifically using neural networks. Here, decoy discrimination is represent...
Ching-Wai Tan, David T. Jones