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BMCBI
2005
87views more  BMCBI 2005»
13 years 8 months ago
ProfNet, a method to derive profile-profile alignment scoring functions that improves the alignments of distantly related protei
Background: Profile-profile methods have been used for some years now to detect and align homologous proteins. The best such methods use information from the background distributi...
Tomas Ohlson, Arne Elofsson
BMCBI
2008
114views more  BMCBI 2008»
13 years 8 months ago
Indel PDB: A database of structural insertions and deletions derived from sequence alignments of closely related proteins
Background: Insertions and deletions (indels) represent a common type of sequence variations, which are less studied and pose many important biological questions. Recent research ...
Michael Hsing, Artem Cherkasov
BMCBI
2005
118views more  BMCBI 2005»
13 years 8 months ago
Variation in structural location and amino acid conservation of functional sites in protein domain families
Background: The functional sites of a protein present important information for determining its cellular function and are fundamental in drug design. Accordingly, accurate methods...
Birgit Pils, Richard R. Copley, Jörg Schultz
NAR
2002
132views more  NAR 2002»
13 years 8 months ago
euGenes: a eukaryote genome information system
euGenes is a genome information system and database that provides a common summary of eukaryote genes and genomes, at web site http://iubio.bio.indiana.edu/eugenes/. Seven popular...
Donald G. Gilbert
NAR
2010
122views more  NAR 2010»
13 years 3 months ago
ELM: the status of the 2010 eukaryotic linear motif resource
Linear motifs are short segments of multidomain proteins that provide regulatory functions independently of protein tertiary structure. Much of intracellular signalling passes thr...
Cathryn M. Gould, Francesca Diella, Allegra Via, P...