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BMCBI
2010
103views more  BMCBI 2010»
13 years 8 months ago
Prediction of GTP interacting residues, dipeptides and tripeptides in a protein from its evolutionary information
Background: Guanosine triphosphate (GTP)-binding proteins play an important role in regulation of G-protein. Thus prediction of GTP interacting residues in a protein is one of the...
Jagat S. Chauhan, Nitish K. Mishra, Gajendra P. S....
BMCBI
2005
90views more  BMCBI 2005»
13 years 8 months ago
TMB-Hunt: An amino acid composition based method to screen proteomes for beta-barrel transmembrane proteins
Background: Beta-barrel transmembrane (bbtm) proteins are a functionally important and diverse group of proteins expressed in the outer membranes of bacteria (both gram negative a...
Andrew G. Garrow, Alison Agnew, David R. Westhead
BIOCOMP
2008
13 years 10 months ago
Analysis of Protein-Ligand Interactions Using Localized Stereochemical Features
Computational analyses of protein structure-function relationships have traditionally been based on sequence homology, fold family analysis and 3D motifs/templates. Previous struct...
Reetal Pai, James C. Sacchettini, Thomas R. Ioerge...
BMCBI
2006
92views more  BMCBI 2006»
13 years 8 months ago
Similarity-based gene detection: using COGs to find evolutionarily-conserved ORFs
Background: Experimental verification of gene products has not kept pace with the rapid growth of microbial sequence information. However, existing annotations of gene locations c...
Bradford C. Powell, Clyde A. Hutchison III
BMCBI
2007
148views more  BMCBI 2007»
13 years 8 months ago
Blast sampling for structural and functional analyses
Background: The post-genomic era is characterised by a torrent of biological information flooding the public databases. As a direct consequence, similarity searches starting with ...
Anne Friedrich, Raymond Ripp, Nicolas Garnier, Emm...