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» Complete Parsimony Haplotype Inference Problem and Algorithm...
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COCOON
2008
Springer
13 years 10 months ago
Haplotype Inferring Via Galled-Tree Networks Is NP-Complete
The problem of determining haplotypes from genotypes has gained considerable prominence in the research community since the beginning of the HapMap project. Here the focus is on de...
Arvind Gupta, Ján Manuch, Ladislav Stacho, ...
ESA
2001
Springer
105views Algorithms» more  ESA 2001»
14 years 1 months ago
SNPs Problems, Complexity, and Algorithms
Abstract. Single nucleotide polymorphisms (SNPs) are the most frequent form of human genetic variation. They are of fundamental importance for a variety of applications including m...
Giuseppe Lancia, Vineet Bafna, Sorin Istrail, Ross...
ISMB
2000
13 years 10 months ago
A Practical Algorithm for Optimal Inference of Haplotypes from Diploid Populations
The next phase of human genomics will involve largescale screens of populations for signi cant DNA polymorphisms, notably single nucleotide polymorphisms SNP's. Dense human S...
Dan Gusfield
EXPCS
2007
14 years 12 days ago
Performance testing of combinatorial solvers with isomorph class instances
Combinatorial optimization problems expressed as Boolean constraint satisfaction problems (BCSPs) arise in several contexts, ranging from the classical unate set-packing problems ...
Franc Brglez, Jason A. Osborne
CPM
2010
Springer
120views Combinatorics» more  CPM 2010»
14 years 1 months ago
Mod/Resc Parsimony Inference
Abstract. We address in this paper a new computational biology problem that aims at understanding a mechanism that could potentially be used to genetically manipulate natural insec...
Igor Nor, Danny Hermelin, Sylvain Charlat, Jan Eng...