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» Complexity Analysis of Heuristic CSP Search Algorithms
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TKDE
2010
200views more  TKDE 2010»
13 years 6 months ago
Incremental and General Evaluation of Reverse Nearest Neighbors
This paper presents a novel algorithm for Incremental and General Evaluation of continuous Reverse Nearest neighbor queries (IGERN, for short). The IGERN algorithm is general in t...
James M. Kang, Mohamed F. Mokbel, Shashi Shekhar, ...
BMCBI
2010
152views more  BMCBI 2010»
13 years 8 months ago
A high-throughput de novo sequencing approach for shotgun proteomics using high-resolution tandem mass spectrometry
Background: High-resolution tandem mass spectra can now be readily acquired with hybrid instruments, such as LTQ-Orbitrap and LTQ-FT, in high-throughput shotgun proteomics workflo...
Chongle Pan, Byung-Hoon Park, William H. McDonald,...
BMCBI
2008
148views more  BMCBI 2008»
13 years 8 months ago
Critical assessment of alignment procedures for LC-MS proteomics and metabolomics measurements
Background: Liquid chromatography coupled to mass spectrometry (LC-MS) has become a prominent tool for the analysis of complex proteomics and metabolomics samples. In many applica...
Eva Lange, Ralf Tautenhahn, Steffen Neumann, Cleme...
GECCO
2009
Springer
14 years 2 months ago
On the performance effects of unbiased module encapsulation
A recent theoretical investigation of modular representations shows that certain modularizations can introduce a distance bias into a landscape. This was a static analysis, and em...
R. Paul Wiegand, Gautham Anil, Ivan I. Garibay, Oz...
GECCO
2010
Springer
191views Optimization» more  GECCO 2010»
14 years 20 days ago
Initialization parameter sweep in ATHENA: optimizing neural networks for detecting gene-gene interactions in the presence of sma
Recent advances in genotyping technology have led to the generation of an enormous quantity of genetic data. Traditional methods of statistical analysis have proved insufficient i...
Emily Rose Holzinger, Carrie C. Buchanan, Scott M....