23098 search results - page 4560 / 4620 » Component Based Development |
BMCBI
2005
13 years 9 months ago
2005
Background: The large gap between the number of protein sequences in databases and the number of functionally characterized proteins calls for the development of a fast computatio...
BMCBI
2005
13 years 9 months ago
2005
Background: Two central problems in computational biology are the determination of the alignment and phylogeny of a set of biological sequences. The traditional approach to this p...
BMCBI
2005
13 years 9 months ago
2005
Background: Cis-regulatory modules are combinations of regulatory elements occurring in close proximity to each other that control the spatial and temporal expression of genes. Th...
BMCBI
2005
13 years 9 months ago
2005
Background: The availability of the human genome sequence as well as the large number of physically accessible oligonucleotides, cDNA, and BAC clones across the entire genome has ...
BMCBI
2005
13 years 9 months ago
2005
Background: Alternative splicing is a major mechanism of generating protein diversity in higher eukaryotes. Although at least half, and probably more, of mammalian genes are alter...