Background: Computer programs for the generation of multiple sequence alignments such as "Clustal W" allow detection of regions that are most conserved among many sequen...
Olga V. Matveeva, Brian T. Foley, Vladimir A. Nemt...
Background: Parallel computing is frequently used to speed up computationally expensive tasks in Bioinformatics. Results: Herein, a parallel version of the multi-alignment program...
Martin Schmollinger, Kay Nieselt, Michael Kaufmann...
Background: Recent technological advances in high-throughput data collection allow for experimental study of increasingly complex systems on the scale of the whole cellular genome...
Bahrad A. Sokhansanj, J. Patrick Fitch, Judy N. Qu...
Background: Eukaryotic whole genome sequences are accumulating at an impressive rate. Effective methods for comparing multiple whole eukaryotic genomes on a large scale are needed...
Solid modeling based on partial differential equations (PDEs) can potentially unify both geometric constraints and functional requirements within a single design framework to mode...