23098 search results - page 4594 / 4620 » Component Based Development |
ANOR
2011
13 years 2 months ago
2011
Hard problems for metaheuristic search can be a source of insight for developing better methods. We examine a challenging instance of such a problem that has exactly two local opt...
BMCBI
2010
13 years 2 months ago
2010
Background: The functional and structural characterisation of enzymes that belong to microbial metabolic pathways is very important for structure-based drug design. The main inter...
BMCBI
2010
13 years 2 months ago
2010
Background: Elucidating protein-protein interactions (PPIs) is essential to constructing protein interaction networks and facilitating our understanding of the general principles ...
BMCBI
2010
13 years 2 months ago
2010
Background: Differential co-expression analysis is an emerging strategy for characterizing disease related dysregulation of gene expression regulatory networks. Given pre-defined ...
BMCBI
2010
13 years 2 months ago
2010
Background: Ever since the ground-breaking work of Anfinsen et al. in which a denatured protein was found to refold to its native state, it has been frequently stated by the prote...