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BMCBI
2011
13 years 2 months ago
Support vector machines-based identification of alternative splicing in Arabidopsis thaliana from whole-genome tiling arrays
Background: Alternative splicing (AS) is a process which generates several distinct mRNA isoforms from the same gene by splicing different portions out of the precursor transcript...
Johannes Eichner, Georg Zeller, Sascha Laubinger, ...
BMCBI
2011
13 years 2 months ago
Multiclass classification of microarray data samples with a reduced number of genes
Background: Multiclass classification of microarray data samples with a reduced number of genes is a rich and challenging problem in Bioinformatics research. The problem gets hard...
Elizabeth Tapia, Leonardo Ornella, Pilar Bulacio, ...
BMCBI
2011
13 years 2 months ago
Appearance frequency modulated gene set enrichment testing
Background: Gene set enrichment testing has helped bridge the gap from an individual gene to a systems biology interpretation of microarray data. Although gene sets are defined a ...
Jun Ma, Maureen A. Sartor, H. V. Jagadish
BMCBI
2011
13 years 2 months ago
AnyExpress: Integrated toolkit for analysis of cross-platform gene expression data using a fast interval matching algorithm
Background: Cross-platform analysis of gene express data requires multiple, intricate processes at different layers with various platforms. However, existing tools handle only a s...
Jihoon Kim, Kiltesh Patel, Hyunchul Jung, Winston ...
BMCBI
2011
13 years 2 months ago
pROC: an open-source package for R and S+ to analyze and compare ROC curves
Background: Receiver operating characteristic (ROC) curves are useful tools to evaluate classifiers in biomedical and bioinformatics applications. However, conclusions are often r...
Xavier Robin, Natacha Turck, Alexandre Hainard, Na...
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