Bioinformatics blossomed with research developments in molecular biology. But as the focus of research moves back up the physical scale to the biology of whole multicellular organ...
T. Charles Hodgman, Y. Ugartechea-Chirino, G. Tans...
Background: Over the last few years, genome-wide association (GWA) studies became a tool of choice for the identification of loci associated with complex traits. Currently, impute...
Yurii S. Aulchenko, Maksim V. Struchalin, Cornelia...
Background: Large-scale genetic mapping projects require data management systems that can handle complex phenotypes and detect and correct high-throughput genotyping errors, yet a...
Simon Fiddy, David Cattermole, Dong Xie, Xiao Yuan...
Background: Post-translational modifications have a substantial influence on the structure and functions of protein. Post-translational phosphorylation is one of the most common m...
Paul D. Yoo, Yung Shwen Ho, Bing Bing Zhou, Albert...
Middleware facilitates the development of distributed systems by accommodating heterogeneity, hiding distribution details and providing a set of common and domain specific service...