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BMCBI
2006
82views more  BMCBI 2006»
13 years 7 months ago
Selection of antisense oligonucleotides based on multiple predicted target mRNA structures
Background: Local structures of target mRNAs play a significant role in determining the efficacies of antisense oligonucleotides (ODNs), but some structure-based target site selec...
Xiaochen Bo, Shaoke Lou, Daochun Sun, Wenjie Shu, ...
GEOINFORMATICA
2008
123views more  GEOINFORMATICA 2008»
13 years 7 months ago
Efficient Implementation Techniques for Topological Predicates on Complex Spatial Objects
Topological relationships like overlap, inside, meet, and disjoint uniquely characterize the relative position between objects in space. For a long time, they have been a focus of...
Reasey Praing, Markus Schneider
BMCBI
2006
138views more  BMCBI 2006»
13 years 7 months ago
Approximation properties of haplotype tagging
Background: Single nucleotide polymorphisms (SNPs) are locations at which the genomic sequences of population members differ. Since these differences are known to follow patterns,...
Staal A. Vinterbo, Stephan Dreiseitl, Lucila Ohno-...
BMCBI
2006
100views more  BMCBI 2006»
13 years 7 months ago
Towards a better solution to the shortest common supersequence problem: the deposition and reduction algorithm
Background: The problem of finding a Shortest Common Supersequence (SCS) of a set of sequences is an important problem with applications in many areas. It is a key problem in biol...
Kang Ning, Hon Wai Leong
BMCBI
2006
78views more  BMCBI 2006»
13 years 7 months ago
An evaluation of human protein-protein interaction data in the public domain
Background: Protein-protein interaction (PPI) databases have become a major resource for investigating biological networks and pathways in cells. A number of publicly available re...
Suresh Mathivanan, Balamurugan Periaswamy, T. K. B...
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