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ALMOB
2006
106views more  ALMOB 2006»
13 years 9 months ago
Multiple sequence alignment with user-defined anchor points
Background: Automated software tools for multiple alignment often fail to produce biologically meaningful results. In such situations, expert knowledge can help to improve the qua...
Burkhard Morgenstern, Sonja J. Prohaska, Dirk P&ou...
FSS
2008
130views more  FSS 2008»
13 years 9 months ago
A fuzzy k-partitions model for categorical data and its comparison to the GoM model
The grade of membership (GoM) model uses fuzzy sets as memberships of each individual to extreme profiles (or classes) on the likelihood function of multivariate multinomial distr...
Miin-Shen Yang, Yu-Hsuan Chiang, Chiu-Chi Chen, Ch...
BMCBI
2006
115views more  BMCBI 2006»
13 years 9 months ago
SimArray: a user-friendly and user-configurable microarray design tool
Background: Microarrays were first developed to assess gene expression but are now also used to map protein-binding sites and to assess allelic variation between individuals. Rega...
Richard P. Auburn, Roslin R. Russell, Bettina Fisc...
BMCBI
2006
169views more  BMCBI 2006»
13 years 9 months ago
Finding biological process modifications in cancer tissues by mining gene expression correlations
Background: Through the use of DNA microarrays it is now possible to obtain quantitative measurements of the expression of thousands of genes from a biological sample. This techno...
Giacomo Gamberoni, Sergio Storari, Stefano Volinia
BMCBI
2006
179views more  BMCBI 2006»
13 years 9 months ago
Multiscale Hy3S: Hybrid stochastic simulation for supercomputers
Background: Stochastic simulation has become a useful tool to both study natural biological systems and design new synthetic ones. By capturing the intrinsic molecular fluctuation...
Howard Salis, Vassilios Sotiropoulos, Yiannis N. K...
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