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ANSOFT
2002
159views more  ANSOFT 2002»
15 years 2 months ago
Using Component-Based Development and Web Technologies to Support a Distributed Data Management System
Over recent years, "Internet-able" applications have been used to support domains where distributed functionality is essential. This flexibility is also pertinent in situ...
M. Brian Blake, Gail Hamilton, Jeffrey Hoyt
BMCBI
2004
166views more  BMCBI 2004»
15 years 2 months ago
Gene prediction using the Self-Organizing Map: automatic generation of multiple gene models
Background: Many current gene prediction methods use only one model to represent proteincoding regions in a genome, and so are less likely to predict the location of genes that ha...
Shaun Mahony, James O. McInerney, Terry J. Smith, ...
BMCBI
2004
96views more  BMCBI 2004»
15 years 2 months ago
Identification of regions in multiple sequence alignments thermodynamically suitable for targeting by consensus oligonucleotides
Background: Computer programs for the generation of multiple sequence alignments such as "Clustal W" allow detection of regions that are most conserved among many sequen...
Olga V. Matveeva, Brian T. Foley, Vladimir A. Nemt...
BMCBI
2004
97views more  BMCBI 2004»
15 years 2 months ago
Global features of sequences of bacterial chromosomes, plasmids and phages revealed by analysis of oligonucleotide usage pattern
Background: Oligonucleotide frequencies were shown to be conserved signatures for bacterial genomes, however, the underlying constraints have yet not been resolved in detail. In t...
Oleg N. Reva, Burkhard Tümmler
BMCBI
2004
141views more  BMCBI 2004»
15 years 2 months ago
Estimates of statistical significance for comparison of individual positions in multiple sequence alignments
Background: Profile-based analysis of multiple sequence alignments (MSA) allows for accurate comparison of protein families. Here, we address the problems of detecting statistical...
Ruslan Sadreyev, Nick V. Grishin
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