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2000
13 years 9 months ago
Combinatorial Approaches to Finding Subtle Signals in DNA Sequences
Signal nding pattern discovery in unaligned DNA sequences is a fundamental problem in both computer science and molecular biology with important applications in locating regulator...
Pavel A. Pevzner, Sing-Hoi Sze
CIBCB
2009
IEEE
13 years 8 months ago
rnaDesign: Local search for RNA secondary structure design
Abstract-- The RNA secondary structure design (SSD) problem is a recently emerging research topic motivated by applications such as customized drug design and the self-assembly of ...
Denny C. Dai, Herbert H. Tsang, Kay C. Wiese
COMPLIFE
2006
Springer
13 years 11 months ago
Adaptive Approach for Modelling Variability in Pharmacokinetics
Abstract. We present an improved adaptive approach for studying systems of ODEs affected by parameter variability and state space uncertainty. Our approach is based on a reformulat...
Andrea Y. Weiße, Illia Horenko, Wilhelm Huis...
WABI
2007
Springer
14 years 1 months ago
Shotgun Protein Sequencing
Although snake venom proteins have been proven instrumental in the design of blood clotting and cytostatic breast cancer drugs, the main method in use to sequence these unknown pr...
Pavel A. Pevzner
IPPS
2006
IEEE
14 years 1 months ago
Parallelization and performance characterization of protein 3D structure prediction of Rosetta
The prediction of protein 3D structure has become a hot research area in the post-genome era, through which people can understand a protein’s function in health and disease, exp...
Wenlong Li, Tao Wang, Eric Li, D. Baker, Li Jin, S...