This paper studies various algorithmic issues in reconstructing a species tree from gene trees under the duplication and the mutation cost model. This is a fundamental problem in c...
The emergence of high-throughput technologies for measuring biological systems has introduced problems for data interpretation that must be addressed for proper inference. First, ...
The world wide web(WWW)has becomecritical for storing and disseminatingbiological data. It offers an additional opportunity, however,to support distributed computation and sharing...
Richard O. Chen, Ramon M. Felciano, Russ B. Altman
Our major effort in this reporting period comprised functional genomic studies of key genes for carbon metabolite and nodulation/nitrogen fixation in Sinorhizobium meliloti, compar...
We study from a computational standpoint several different physicalscales associatedwith structural features of DNA sequences, including dinucleotide scales such as base stacking ...