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130
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SIAMCOMP
2000
90views more  SIAMCOMP 2000»
15 years 3 months ago
From Gene Trees to Species Trees
This paper studies various algorithmic issues in reconstructing a species tree from gene trees under the duplication and the mutation cost model. This is a fundamental problem in c...
Bin Ma, Ming Li, Louxin Zhang
133
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BIB
2010
89views more  BIB 2010»
15 years 3 months ago
Knowledge-based data analysis comes of age
The emergence of high-throughput technologies for measuring biological systems has introduced problems for data interpretation that must be addressed for proper inference. First, ...
Michael F. Ochs
110
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ISMB
1997
15 years 5 months ago
RIBOWEB: Linking Structural Computations to a Knowledge Base of Published Experimental Data
The world wide web(WWW)has becomecritical for storing and disseminatingbiological data. It offers an additional opportunity, however,to support distributed computation and sharing...
Richard O. Chen, Ramon M. Felciano, Russ B. Altman
ISMB
2007
15 years 6 months ago
Computational prediction of host-pathogen protein-protein interactions
Our major effort in this reporting period comprised functional genomic studies of key genes for carbon metabolite and nodulation/nitrogen fixation in Sinorhizobium meliloti, compar...
Matthew D. Dyer, T. M. Murali, Bruno W. S. Sobral
148
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ISMB
1998
15 years 5 months ago
Computational Applications of DNA Structural Scales
We study from a computational standpoint several different physicalscales associatedwith structural features of DNA sequences, including dinucleotide scales such as base stacking ...
Pierre Baldi, Søren Brunak, Yves Chauvin, A...