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ISMB
1994
15 years 6 months ago
Optimally Parsing a Sequence into Different Classes Based on Multiple Types of Evidence
Weconsider the problem of parsing a sequence into different classes of subsequences.Twocommonexamplesare finding the exons and introns in genomicsequences and identifying the seco...
Gary D. Stormo, David Haussler
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ISMB
1993
15 years 6 months ago
Representation for Discovery of Protein Motifs
There are several dimensions and levels of complexity in which information on protein motifs may be available. For example, onedimensional sequence motifs may be associated with s...
Darrell Conklin, Suzanne Fortier, Janice I. Glasgo...
ISMB
1993
15 years 6 months ago
Using Dirichlet Mixture Priors to Derive Hidden Markov Models for Protein Families
A Bayesian method for estimating the amino acid distributions in the states of a hidden Markov model (HMM) for a protein familyor the columns of a multiple alignment of that famil...
Michael Brown, Richard Hughey, Anders Krogh, I. Sa...
ISMB
1993
15 years 6 months ago
Protein Classification Using Neural Networks
Wehave recently described a method based on Artificial Neural Networksto cluster protein sequences into families. The network was trained with Kohonen’s unsupervised-learning al...
Edgardo A. Ferrán, Pascual Ferrara, Bernard...
ISMB
1993
15 years 6 months ago
Prediction of Primate Splice Junction Gene Sequences with a Cooperative Knowledge Acquisition System
Wepropose a cooperative conceptual modelling environment in which two agents interact : the machineand the humanexpert. Theformer is able to extract knowledge from data using a sy...
Engelbert Mephu Nguifo, Jean Sallantin