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BMCBI
2006
153views more  BMCBI 2006»
13 years 8 months ago
Discovery of time-delayed gene regulatory networks based on temporal gene expression profiling
Background: It is one of the ultimate goals for modern biological research to fully elucidate the intricate interplays and the regulations of the molecular determinants that prope...
Xia Li, Shaoqi Rao, Wei Jiang, Chuanxing Li, Yun X...
GPEM
2008
128views more  GPEM 2008»
13 years 8 months ago
Coevolutionary bid-based genetic programming for problem decomposition in classification
In this work a cooperative, bid-based, model for problem decomposition is proposed with application to discrete action domains such as classification. This represents a significan...
Peter Lichodzijewski, Malcolm I. Heywood
BMCBI
2006
127views more  BMCBI 2006»
13 years 8 months ago
Improvement in the Reproducibility and Accuracy of DNA Microarray Quantification by Optimizing Hybridization Conditions
Background: DNA microarrays, which have been increasingly used to monitor mRNA transcripts at a global level, can provide detailed insight into cellular processes involved in resp...
Tao Han, Cathy D. Melvin, Leming M. Shi, William S...
BMCBI
2006
91views more  BMCBI 2006»
13 years 8 months ago
Cheminformatics methods for novel nanopore analysis of HIV DNA termini
Background: Channel current feature extraction methods, using Hidden Markov Models (HMMs) have been designed for tracking individual-molecule conformational changes. This informat...
Stephen Winters-Hilt, Matthew Landry, Mark Akeson,...
BMCBI
2006
129views more  BMCBI 2006»
13 years 8 months ago
EGenBio: A Data Management System for Evolutionary Genomics and Biodiversity
Background: Evolutionary genomics requires management and filtering of large numbers of diverse genomic sequences for accurate analysis and inference on evolutionary processes of ...
Laila A. Nahum, Matthew T. Reynolds, Zhengyuan O. ...
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