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BMCBI
2006
122views more  BMCBI 2006»
13 years 8 months ago
Computational reconstruction of transcriptional regulatory modules of the yeast cell cycle
Background: A transcriptional regulatory module (TRM) is a set of genes that is regulated by a common set of transcription factors (TFs). By organizing the genome into TRMs, a liv...
Wei-Sheng Wu, Wen-Hsiung Li, Bor-Sen Chen
ISMB
1997
13 years 10 months ago
Adding Semantics to Genome Databases: Towards an Ontology for Molecular Biology
Molecular biology has a communicationproblem. There are manydatabases using their ownlabels and categories for storing data objects and someusing identical labels andcategories bu...
Steffen Schulze-Kremer
RECOMB
2001
Springer
14 years 8 months ago
Context-specific Bayesian clustering for gene expression data
The recent growth in genomic data and measurements of genome-wide expression patterns allows us to apply computational tools to examine gene regulation by transcription factors. I...
Yoseph Barash, Nir Friedman
BMCBI
2010
219views more  BMCBI 2010»
13 years 3 months ago
BiologicalNetworks 2.0 - an integrative view of genome biology data
Background: A significant problem in the study of mechanisms of an organism's development is the elucidation of interrelated factors which are making an impact on the differe...
Sergey Kozhenkov, Yulia Dubinina, Mayya Sedova, Am...
BIODATAMINING
2008
130views more  BIODATAMINING 2008»
13 years 8 months ago
Uncovering mechanisms of transcriptional regulations by systematic mining of cis regulatory elements with gene expression profil
Background: Contrary to the traditional biology approach, where the expression patterns of a handful of genes are studied at a time, microarray experiments enable biologists to st...
Qicheng Ma, Gung-Wei Chirn, Joseph D. Szustakowski...