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BIOINFORMATICS
2010
138views more  BIOINFORMATICS 2010»
13 years 8 months ago
Robust unmixing of tumor states in array comparative genomic hybridization data
Motivation: Tumorigenesis is an evolutionary process by which tumor cells acquire sequences of mutations leading to increased growth, invasiveness, and eventually metastasis. It i...
David Tolliver, Charalampos E. Tsourakakis, Ayshwa...
BMEI
2008
IEEE
14 years 3 months ago
A New Approach for Tree Alignment Based on Local Re-Optimization
Multiple sequence alignment is the most fundamental task in bioinformatics and computational biology. In this paper, we present a new algorithm to conduct multiple sequences align...
Feng Yue, Jijun Tang
BMCBI
2008
79views more  BMCBI 2008»
13 years 8 months ago
A high-throughput pipeline for designing microarray-based pathogen diagnostic assays
Background: We present a methodology for high-throughput design of oligonucleotide fingerprints for microarray-based pathogen diagnostic assays. The oligonucleotide fingerprints, ...
Ravi Vijaya Satya, Nela Zavaljevski, Kamal Kumar, ...
ESA
2001
Springer
105views Algorithms» more  ESA 2001»
14 years 1 months ago
SNPs Problems, Complexity, and Algorithms
Abstract. Single nucleotide polymorphisms (SNPs) are the most frequent form of human genetic variation. They are of fundamental importance for a variety of applications including m...
Giuseppe Lancia, Vineet Bafna, Sorin Istrail, Ross...
ESWA
2006
148views more  ESWA 2006»
13 years 8 months ago
Applications of artificial intelligence in bioinformatics: A review
Artificial intelligence (AI) has increasingly gained attention in bioinformatics research and computational molecular biology. With the availability of different types of AI algor...
Zoheir Ezziane