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BMCBI
2004
96views more  BMCBI 2004»
13 years 8 months ago
Identification of regions in multiple sequence alignments thermodynamically suitable for targeting by consensus oligonucleotides
Background: Computer programs for the generation of multiple sequence alignments such as "Clustal W" allow detection of regions that are most conserved among many sequen...
Olga V. Matveeva, Brian T. Foley, Vladimir A. Nemt...
BMCBI
2008
132views more  BMCBI 2008»
13 years 8 months ago
The Average Mutual Information Profile as a Genomic Signature
Background: Occult organizational structures in DNA sequences may hold the key to understanding functional and evolutionary aspects of the DNA molecule. Such structures can also p...
Mark Bauer, Sheldon M. Schuster, Khalid Sayood
DNA
2003
Springer
101views Bioinformatics» more  DNA 2003»
14 years 1 months ago
A Lab-on-a-Chip Module for Bead Separation in DNA-Based Concept Learning
Affinity separation with magnetic beads is an important and widely used technique for DNA computing. We have designed and implemented an experimental lab-on-a-chip module for affin...
Hee-Woong Lim, Hae-Man Jang, Sung-Mo Ha, Young-Gyu...
RECOMB
2005
Springer
14 years 9 months ago
Improved Pattern-Driven Algorithms for Motif Finding in DNA Sequences
Abstract. In order to guarantee that the optimal motif is found, traditional pattern-driven approaches perform an exhaustive search over all candidate motifs of length l. We develo...
Sing-Hoi Sze, Xiaoyan Zhao
RECOMB
2008
Springer
14 years 9 months ago
CompostBin: A DNA Composition-Based Algorithm for Binning Environmental Shotgun Reads
A major hindrance to studies of microbial diversity has been that the vast majority of microbes cannot be cultured in the laboratory and thus are not amenable to traditional method...
Sourav Chatterji, Ichitaro Yamazaki, Zhaojun Bai, ...