Background: Microarray expression profiling has been widely used to identify differentially expressed genes in complex cellular systems. However, while such methods can be used to...
Background: Recent genomic scale survey of epigenetic states in the mammalian genomes has shown that promoters and enhancers are correlated with distinct chromatin signatures, pro...
Kyoung-Jae Won, Iouri Chepelev, Bing Ren, Wei Wang
We present a fast variational deconvolution algorithm that minimizes a quadratic data term subject to a regularization on the 1 -norm of the wavelet coefficients of the solution. ...
Alternative splicing (AS) is an important and frequent step in mammalian gene expression that allows a single gene to specify multiple products, and is crucial for the regulation ...
Ofer Shai, Brendan J. Frey, Quaid Morris, Qun Pan,...
Abstract. We investigate the evolutionary processes behind the development and optimization of multiple threads of execution in digital organisms using the avida platform, a softwa...
Charles Ofria, Christoph Adami, Travis C. Collier,...