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BMCBI
2008
13 years 10 months ago
2008
Background: DNA microarrays contain thousands of different probe sequences represented on their surface. These are designed in such a way that potential cross-hybridization reacti...
CCR
2008
13 years 10 months ago
2008
Despite the flurry of anomaly-detection papers in recent years, effective ways to validate and compare proposed solutions have remained elusive. We argue that evaluating anomaly d...
BMCBI
2006
13 years 9 months ago
2006
Background: A great deal of effort and expense are being expended internationally in attempts to detect genetic polymorphisms contributing to susceptibility to complex human disea...
BMCBI
2006
13 years 9 months ago
2006
Background: Various experimental techniques yield peptides that are biologically active but have unfavourable pharmacological properties. The design of structurally similar organi...
BMCBI
2006
13 years 9 months ago
2006
Background: Stochastic simulation has become a useful tool to both study natural biological systems and design new synthetic ones. By capturing the intrinsic molecular fluctuation...