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BMCBI
2010
112views more  BMCBI 2010»
13 years 8 months ago
A boundary delimitation algorithm to approximate cell soma volumes of bipolar cells from topographical data obtained by scanning
Background: Cell volume determination plays a pivotal role in the investigation of the biophysical mechanisms underlying various cellular processes. Whereas light microscopy in pr...
Patrick Happel, Kerstin Moller, Ralf Kunz, Irmgard...
BMCBI
2010
118views more  BMCBI 2010»
13 years 8 months ago
svdPPCS: an effective singular value decomposition-based method for conserved and divergent co-expression gene module identifica
Background: Comparative analysis of gene expression profiling of multiple biological categories, such as different species of organisms or different kinds of tissue, promises to e...
Wensheng Zhang, Andrea Edwards, Wei Fan, Dongxiao ...
BMCBI
2010
84views more  BMCBI 2010»
13 years 8 months ago
A variational Bayes algorithm for fast and accurate multiple locus genome-wide association analysis
Background: The success achieved by genome-wide association (GWA) studies in the identification of candidate loci for complex diseases has been accompanied by an inability to expl...
Benjamin A. Logsdon, Gabriel E. Hoffman, Jason G. ...
BMCBI
2010
125views more  BMCBI 2010»
13 years 8 months ago
NeatMap - non-clustering heat map alternatives in R
Background: The clustered heat map is the most popular means of visualizing genomic data. It compactly displays a large amount of data in an intuitive format that facilitates the ...
Satwik Rajaram, Yoshi Oono
BMCBI
2010
89views more  BMCBI 2010»
13 years 8 months ago
Spatial normalization improves the quality of genotype calling for Affymetrix SNP 6.0 arrays
Background: Microarray measurements are susceptible to a variety of experimental artifacts, some of which give rise to systematic biases that are spatially dependent in a unique w...
High-Seng Chai, Terry M. Therneau, Kent R. Bailey,...
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