8 search results - page 1 / 2 » Computing Knock-Out Strategies in Metabolic Networks |
JCB
2008
13 years 11 months ago
2008
Given a metabolic network in terms of its metabolites and reactions, our goal is to efficiently compute the minimal knock out sets of reactions required to block a given behaviour....
BMCBI
2008
13 years 11 months ago
2008
Background: Cellular metabolism is one of the most investigated system of biological interactions. While the topological nature of individual reactions and pathways in the network...
BMCBI
2008
13 years 11 months ago
2008
Background: Metabolic networks present a complex interconnected structure, whose understanding is in general a non-trivial task. Several formal approaches have been developed to s...
BCB
2010
13 years 6 months ago
2010
As a metabolic network reaches from a state to a steady state, a subset of its fluxes gradually change. The sequence of intermediate states, called the dynamic state, shows the pa...
CEC
2010
IEEE
13 years 6 months ago
2010
IEEE
High-throughput analytical techniques such as nuclear magnetic resonance, protein kinase phosphorylation, and mass spectroscopic methods generate time dense profiles of metabolites...