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BMCBI
2008
135views more  BMCBI 2008»
13 years 7 months ago
Identification of a small optimal subset of CpG sites as bio-markers from high-throughput DNA methylation profiles
Background: DNA methylation patterns have been shown to significantly correlate with different tissue types and disease states. High-throughput methylation arrays enable large-sca...
Hailong Meng, Edward Lenn Murrelle, Guoya Li
BMCBI
2010
134views more  BMCBI 2010»
13 years 7 months ago
R-Gada: a fast and flexible pipeline for copy number analysis in association studies
Background: Genome-wide association studies (GWAS) using Copy Number Variation (CNV) are becoming a central focus of genetic research. CNVs have successfully provided target genom...
Roger Pique-Regi, Alejandro Cáceres, Juan R...
BMCBI
2008
100views more  BMCBI 2008»
13 years 7 months ago
PatternLab for proteomics: a tool for differential shotgun proteomics
Background: A goal of proteomics is to distinguish between states of a biological system by identifying protein expression differences. Liu et al. demonstrated a method to perform...
Paulo C. Carvalho, Juliana S. G. Fischer, Emily I....
BMCBI
2008
160views more  BMCBI 2008»
13 years 7 months ago
Predicting cancer involvement of genes from heterogeneous data
Background: Systematic approaches for identifying proteins involved in different types of cancer are needed. Experimental techniques such as microarrays are being used to characte...
Ramon Aragues, Chris Sander, Baldo Oliva
BMCBI
2008
98views more  BMCBI 2008»
13 years 7 months ago
PredGPI: a GPI-anchor predictor
Background: Several eukaryotic proteins associated to the extracellular leaflet of the plasma membrane carry a Glycosylphosphatidylinositol (GPI) anchor, which is linked to the C-...
Andrea Pierleoni, Pier Luigi Martelli, Rita Casadi...