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» Computing and using residuals in time series models
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BMCBI
2010
82views more  BMCBI 2010»
13 years 7 months ago
Predicting the network of substrate-enzyme-product triads by combining compound similarity and functional domain composition
Background: Metabolic pathway is a highly regulated network consisting of many metabolic reactions involving substrates, enzymes, and products, where substrates can be transformed...
Lei Chen, Kai-Yan Feng, Yu-Dong Cai, Kuo-Chen Chou...
BMCBI
2006
111views more  BMCBI 2006»
13 years 7 months ago
High throughput profile-profile based fold recognition for the entire human proteome
Background: In order to maintain the most comprehensive structural annotation databases we must carry out regular updates for each proteome using the latest profile-profile fold r...
Liam J. McGuffin, Richard T. Smith, Kevin Bryson, ...
JCNS
2000
104views more  JCNS 2000»
13 years 7 months ago
Subthreshold Voltage Noise Due to Channel Fluctuations in Active Neuronal Membranes
Abstract. Voltage-gated ion channels in neuronal membranes fluctuate randomly between different conformational states due to thermal agitation. Fluctuations between conducting and ...
Peter N. Steinmetz, Amit Manwani, Christof Koch, M...
DAC
2005
ACM
14 years 8 months ago
StressTest: an automatic approach to test generation via activity monitors
The challenge of verifying a modern microprocessor design is an overwhelming one: Increasingly complex micro-architectures combined with heavy time-to-market pressure have forced ...
Ilya Wagner, Valeria Bertacco, Todd M. Austin
SIGMOD
2006
ACM
145views Database» more  SIGMOD 2006»
14 years 7 months ago
Automatic client-server partitioning of data-driven web applications
Current application development tools provide completely different programming models for the application server (e.g., Java and J2EE) and the client web browser (e.g., JavaScript...
Nicholas Gerner, Fan Yang 0002, Alan J. Demers, Jo...