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» Computing in Solvable Matrix Groups
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BMCBI
2010
144views more  BMCBI 2010»
13 years 9 months ago
Super-sparse principal component analyses for high-throughput genomic data
Background: Principal component analysis (PCA) has gained popularity as a method for the analysis of highdimensional genomic data. However, it is often difficult to interpret the ...
Donghwan Lee, Woojoo Lee, Youngjo Lee, Yudi Pawita...
BMCBI
2010
154views more  BMCBI 2010»
13 years 9 months ago
Binary image representation of a ligand binding site: its application to efficient sampling of a conformational ensemble
Background: Modelling the ligand binding site of a protein is an important component of understanding proteinligand interactions and is being actively studied. Even if the side ch...
Edon Sung, Sangsoo Kim, Whanchul Shin
BMCBI
2005
94views more  BMCBI 2005»
13 years 9 months ago
Measuring similarities between transcription factor binding sites
Background: Collections of transcription factor binding profiles (Transfac, Jaspar) are essential to identify regulatory elements in DNA sequences. Subsets of highly similar profi...
Szymon M. Kielbasa, Didier Gonze, Hanspeter Herzel
COR
2007
106views more  COR 2007»
13 years 9 months ago
On a stochastic sequencing and scheduling problem
We present a framework for solving multistage pure 0–1 programs for a widely used sequencing and scheduling problem with uncertainty in the objective function coefficients, the...
Antonio Alonso-Ayuso, Laureano F. Escudero, M. Ter...
BMCBI
2011
13 years 4 months ago
A novel approach to the clustering of microarray data via nonparametric density estimation
Background: Cluster analysis is a crucial tool in several biological and medical studies dealing with microarray data. Such studies pose challenging statistical problems due to di...
Riccardo De Bin, Davide Risso